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Buprenorphine Topics concerning buprenorphine (subutex, suboxone, buprenex, temgesic) should be posted here. Please use the appropriate sub-forums for posting about supply and online resources for bup.

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Old 10-18-2007, 05:14 PM   #1
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Question Morphine Injections after Suboxone?

I have been on suboxone for about 6 months now, having weaned myself from 24 mg per day to 12 mg per day at this point. However, I obtained 5 60 mg Morphine tablets, a clean needle, and an urge to get ripped. How long do I have to wait if I've taken like 10 mg in the past 36 hours before I should slam that morphine into my favorite vein? I figure since I'm banging it might just overwhelm the small amount of suboxone in my system. Anyone with experience, please help, I would appreciate it very much and you can rest easy knowing you are keeping me high as this smilie looks: (and safe to of course)!


I should note that I have posted identical threads in both the morphine and buprenorphine sections of the forums, I hope I don't seem redundant or annoying but this is important as I will be shooting the morphine within 24 hours.

Love all you guys you helped me through the worst times of my life (vicodin/heroin/oxycontin addiction) and I love the community you have formed, you should be fuckin proud of yourselves. Although I don't visit much, I respect this community very much and empathize with those of you in pain or reaching out for help. Just know you're not alone and you are in complete control of your life and what you do with it. Sorry to ramble, I just took some Ecstasy from Amsterdam and hushed a bit but you guys are the shit man!

All of the aforementioned accounts and proposals are, of course, purely hypothetical in nature.
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Old 10-19-2007, 12:43 AM   #2
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Default Re: Morphine Injections after Suboxone?

based on my personal experience using subbies and morph side by side, if you use subs regularly ur body gets rid of it faster, if you only had 10mg in the last 36hrs (even if it was IV) i say smash the morph BUT have a bit extra to compensate. morph can be felt almost to its full extent on top of subs. if i have subs in my system i just crush two pills instead of one and everything is rosey.

but dont try it the other way, always wait at least 24hrs after morph before having subs
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Old 10-19-2007, 01:44 AM   #3
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Default Re: Morphine Injections after Suboxone?

Any dose of Bupe over 8mg causes a blockade. I would wait 48-72 hours after the last dose of bupe before trying to use ay opiates, especially since you are on a high dose.
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Old 10-19-2007, 02:19 AM   #4
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Default Re: Morphine Injections after Suboxone?

it would block if you tried using morph right away, but i have found from experience that after 24hrs (i never have more than 12mg of bupe btw) i feel my usual dose of morph (admittedly its more like 80% sedation and euphoria with a more pronounced itch/burn/physical sensation ) and i can get high as all fuck by doubling it. after 48hrs its " atchoo!! *sniff* what bupe? *sniff* "

i know your not SUPPOSED to feel morph after bupe, but you can and we do.
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Old 10-19-2007, 04:27 AM   #5
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Default Re: Morphine Injections after Suboxone?

Those blocking things are always very very subjective or individual things. I was able to get high very well after 24 hours, quite well yet after 12 hours. And my dose was 24 mg.
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Old 10-19-2007, 04:32 AM   #6
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Default Re: Morphine Injections after Suboxone?

I kind of agree with you, on the subjectivity of this thing. Every once in a while, while on subs, I'd get some good NE heroin, and I'd give 24 hrs--I'd do pill every morning, so just wait til next morning, and always got rush...so for me, 24 hrs is good, but again, everybody is different, and if you are *strungout* want to be careful because if you stay well by doing a different opiate, it will all get kicked back out when u do subs again...so PW's are always a risk...but again, everybody seems to figure out what works for them...


Quote:
Originally Posted by Canis aureus View Post
Those blocking things are always very very subjective or individual things. I was able to get high very well after 24 hours, quite well yet after 12 hours. And my dose was 24 mg.
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Old 10-19-2007, 04:56 AM   #7
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Default Re: Morphine Injections after Suboxone?

It is subjective but Roxi is right, 10mg within 24hrs is kind of a lot and pushing the window. He'll probably feel it, the question is how much...
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Old 10-19-2007, 02:19 PM   #8
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Default Re: Morphine Injections after Suboxone?

the mean half life of bupe is 37 hours.... so half of ur last dose will still be in u at 37 hours.....
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Old 10-19-2007, 09:04 PM   #9
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Default Re: Morphine Injections after Suboxone?

The problem with the 37 hour half life thing is that we tend to take it every 24 hours and I believe it tends to build up in your system. SWIM has been on 8mg suboxone per day for almost 2 years now and lately have been experimenting with oxycontin usage after certain durations of abstinance from suboxone. My suboxone dose has never changed in the 2 years. The first time SWIM tried doing oxy after being on suboxone... about after 1 1/2 years of being on suboxone. SWIM obtained 5 brandname 40s and waited about 80 hours or so... proceeded to rail 40mg which provided a nice little oxy rush but then nothing. So SWIM railed another 60mg and this got him feeling pretty euphoric. Several hours had passed and SWIM railed his last 40mg about 6 hours after the initial 40mg and the last 40mg shot pushed the oxy into full effect.

Other experiments since have been obtaining usually 5 40mg oxys but insufflated rather than railed. SWIM's last experiment was to insufflate a 40mg oxy every 24 hours since last 8mg suboxone dosage. At 24 hours since last sub, mild feeling is noted, however no additional amount of oxy will add any additional effect. At 48 hours since last sub, it's the same thing... a mild feeling is noted, but still no additional amount will add any effect. At 72 hours cravings really beginning to set in, but the effects of 40mg were more pronounced however weak. At this point SWIm could no longer wait 24 hours in between doses, so at 84 hours SWIM took his 4th 40mg and it got SWIM high... 6 hours later and SWIM did his final 40mg and had a full blow oxy effect.

Several other attempts such as an 80mg insufflated dose at 60 hours had little effect... My conclusion for insufflation of oxy, for someone who has been on an 8mg dosage for a long while, to get a good efffect a person should wait somewhere between 72 and 96 hours to get full effects.

SWIM's is at 72 hours since last suboxone usage and is about to rail some oxy... He really want's to wait til 84 hours but the chances of that happening or slim and none... unless he were to divide it into 2 doses which might be a smart idea.

Sorry about the lengthy post, but SWIM has really working on these "experiments" to figure out how long a person needs to wait.... A lot of money has been wasted on null or minimal effects. All future experiments will be via I.V. oxy or bags...
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Old 10-19-2007, 09:58 PM   #10
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Default Re: Morphine Injections after Suboxone?

I just wanted to let you all know, SWIM has just conducted another experiment. While most of SWIM's experiments have been conducted with oxycodone via insufflation, SWIM just conducted an experiment as follows:

Time Since Last Suboxone: 71 hours
Last Suboxone Dosage: 8mg

Drug: Oxycodone (oxycontin brandname 80mg pill)
Method of Injestion: I.V.
Dosage: 40mg Injection, immediately followed by a 2nd 40mg Injection (So, x2 40mg I.V. injections a few minutes apart)
Results: After the first 40mg injection, a mild to moderate oxy rush was noted, followed by mild euphoria. After the 2nd 40mg injection no rush really initially upon injection however effects of the oxy became MUCH more pronounced. Almost immediately nose began to get itchy, eyelids very heavy, keep wanting to nod out.
Conclusion: For oxycodone, 72 hours is long enough to wait for an I.V. injection Based on previous experiments insufflation may require a slightly longer wait. If SWIM were to repeat the experiment, he would use 1 80mg injection instead of 2 40mg injections... SWIM only divided the dose as a precaution in case the suboxone blocking effect was still strong enough to dull the effects too much.

On a side note: clean, brand new needles fresh out of the wrappers were used for each injection.
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Old 10-19-2007, 10:03 PM   #11
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Default Re: Morphine Injections after Suboxone?

I'm one of the lucky few who can dose on my subs, and then have a shot of whatever, and still feel it. I've posted before about my experiences being able to do that, including the time I overdosed because I took too much on top of the Suboxone.

There's no real hard and fast rule about these things. It's entirely up to the individual, and their metabolism and brain chemistry.
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Old 10-19-2007, 10:34 PM   #12
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Default Re: Morphine Injections after Suboxone?

Just out of curiousity, how long have you been on suboxone and what dosage? I'm still trying to understand the whole suboxone blocking thing. I also think perhaps that long term usage of suboxone may cause not only the blocking effect for X number of hours but also a high tolerance. SWIM definitely has a hard time keeping the sick away after he waits long enough to be able to get high on full agonists. Basically once he is able to get a full blown opiate effect, he begins to require frequent doses of a shorter-acting full agonists... I guess that's why Swim never goes off of suboxone longer than 5-6 days tops. Even that long of a break is infrequent.
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Old 10-20-2007, 07:31 PM   #13
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Default Re: Morphine Injections after Suboxone?

Quote:
Originally Posted by laudaphun View Post
Just out of curiousity, how long have you been on suboxone and what dosage? I'm still trying to understand the whole suboxone blocking thing. I also think perhaps that long term usage of suboxone may cause not only the blocking effect for X number of hours but also a high tolerance. SWIM definitely has a hard time keeping the sick away after he waits long enough to be able to get high on full agonists. Basically once he is able to get a full blown opiate effect, he begins to require frequent doses of a shorter-acting full agonists... I guess that's why Swim never goes off of suboxone longer than 5-6 days tops. Even that long of a break is infrequent.

Was that question directed to me? I'll answer on the assumption that it was - if it wasn't, well, maybe my info will be useful anyway.

I'm on 12mg Suboxone, and have been on it for three months now. I dose every second day, utilising the extended time the dosage lasts, instead of it having more effect, by taking 24mg. It means I don't have to turn up to the dosing clinic every day (here, Suboxone is usually distributed at the same clinic as methadone) and I have a bit more flexibility.

I dosed today, 24mg (so I won't have to get up early tomorrow to go to the clinic) and this evening I had about 60mg Oxycontin IV. While the rush isn't as strong as it was before I had a habit, and my tolerance obviously being maintained by Suboxone, I definitely felt it, got the taste in my mouth and feel quite comfortable right now.

I've been able to use on top of Suboxone right from the beginning, and I think I'm just one of the rare few who doesn't get the blocking effect. Like I mentioned, I overdosed IVing 100mg MS Contin on top of the 24mg Suboxone. Had never done that before, even as a beginner or when I progressed to Heroin. It was definitely an experience.

Anyway, if your question wasn't directed at me, excuse me for this (probably) boring post
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Old 10-21-2007, 02:48 AM   #14
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Default Re: Morphine Injections after Suboxone?

Yes, my question was directed at you. And WOW! 24mg suboxone, I'm surprised you can feel anything. I know the original thread topic was specific to morphine and suboxone, but I'd imagine if the average joe was able to feel anything on top of suboxone, it would be I.V. morphine... even if it was only a little rush. SWIM has never experiemented with morphine after using suboxone... only oxy and heroin, both of which get blocked for quite awhile at least in his case.

I've read that people can overdose if they are trying to get high by using a full agonist and keep using more and more while the suboxone blockade is fading... then it is gone and all of a sudden the receptors are overwelmed by the mass amount of opiates no longer blocked. I think I read that on the suboxone package insert
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Old 10-21-2007, 02:55 AM   #15
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Default Re: Morphine Injections after Suboxone?

To me, one of the major problems, of having a little knowledge about "half-life" and "blocking" and other terms we now throw around...is that it can lull us into thinking we can predict accurately what a drug will now do in our own bodies, and how safe it is. To me, it's bullshit. Everybody's so different, and our bodies process drugs so differently. I mean I've had personal experience, of one junky on the same dose of methadone, me, overdosing, while my pal, on same dose, for same length of time, pretty much, took me to the hospital. It's *so* subjective and dependent upon body types and intangible factors to be almost useless, and why I worry when we give out numbers and facts and figures as tho that will protect you when you dial out, or ensure a buzz, when we haven't got a clue... You better learn your own tolerance and limits, thru personal experience and observation, and be very skeptical of anything we post on here, just because it sounds learned...
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